At ORNL

  • Close D, Cooper CJ, Wang X, Chirania P, Gupta M, Ossyra JR, Giannone RJ, Engle NL, Tschaplinski TJ, Smith JC, Hedstrom L, Parks JM, and Michener JK*, Horizontal transfer of a pathway for coumarate catabolism unexpectedly inhibits purine nucleotide biosynthesis. Mol Microbiol 2019. Link
  • Millet LJ, Velez JM, and Michener JK*. Genetic selection for small molecule production in competitive microfluidic droplets. ACS Synth Biol. Link.
  • Trofimov AA, Pawlicki AA, Borodinov N, Mandal S, Mathews TJ, Hildebrand M, Ziatdinov MA, Hausladen KA, Urbanowicz PK, Steed CA, Ievlev AV, Belianinov A, Michener JK, Vasudevan R, and Ovchinnikova OS*. Deep data analytics for genetic engineering of diatoms linking genotype to phenotype via machine learning. npj Comput Mater 2019 5:67. Link.
  • Chaves JE, Presley GN, and Michener JK*, Modular engineering of biomass degradation pathways. Processes 2019, 7(4), 230. Link.
  • Cecil JH, Garcia DC, Giannone RJ, and Michener JK*, Rapid, parallel identification of pathways for catabolism of lignin-derived aromatic compounds in Novosphingobium aromaticivorans. Appl Environ Microbiol 2018. 84:e01185-18. Link.
  • Tuskan GA*, Groover AT, Schmutz J, DiFazio SP, Myburg A, Grattapaglia D, Smart L, Yin T, Aury J-M, Kremer A, Leroy T, Le Provost G, Plomion C, Carlson JE, Randall J, Westbrook J, Grimwod J, Muchero W, Jacobson D, and Michener JK, Hardwood tree genomics: Unlocking woody plant biology. Front Plant Sci. 2018; 9: 1799. Link.
  • Standaert RF, Giannone RJ, and Michener JK*. Identification of parallel and divergent optimization solutions for homologous metabolic enzymes. Metab Eng Comm 2018. 6:56-62. Link.
  • Clarkson SM, Giannone RJ, Kridelbaugh DM, Elkins JG, Guss AM*, and Michener JK*, Construction and optimization of a heterologous pathway for protocatechuate catabolism in Escherichia coli enables bioconversion of model aromatic compounds. Appl Env Microbiol 2017 Aug 31;83(18). Link.

Prior to ORNL

  • Michener JK*, Vuilleumier S, Bringel F, and Marx CJ. Transfer of a catabolic pathway for chloromethane in Methylobacterium strains highlights different limitations for growth with chloromethane or with dichloromethane. Front Microbiol 2016. Link
  • Houser JR, Barnhart C, Boutz DR, Carroll SM, Dasgupta A, Michener JK, et al. Controlled measurement and comparative analysis of cellular components in E. coli reveals broad regulatory changes in response to glucose starvation. PLoS Comput Biol 2015; 11(8): e1004400. Link
  • Michener JK, Camargo Neves AAC, Vuilleumier S, Bringel F, and Marx CJ. Effective use of a horizontally-transferred pathway for dichloromethane catabolism requires post-transfer refinement. eLife. 2014;10.7554/eLife.04279 Link.
  • Michener JK, Vuilleumier S, Bringel F, and Marx CJ. Phylogeny poorly predicts the utility of a challenging horizontally-transferred gene in Methylobacterium strains. J Bacteriol., June 2014 196:2101-2107 Link.
  • Michener JK and Smolke CD. Synthetic RNA switches for yeast metabolic engineering. Methods in Molecular Biology, Yeast Metabolic Engineering. 2012; 1152:125-36 Link.
  • Michener JK, Nielsen J, and Smolke CD. Identification and treatment of heme depletion due to over-expression of a lineage of evolved P450 monooxygenases. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19504-9. Link.
  • Michener JK and Smolke CD. High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch. Metabolic Engineering. 2012 Jul; 14(4):306-16. Link
  • Michener JK, Thodey K, Liang JC, and Smolke CD. (2011) Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metabolic Engineering. 2012 May; 14(3):212-22. Link
Biosciences Division, Oak Ridge National Laboratory
1 Bethel Valley Road, Oak Ridge, TN 37830